Weekly Journal of Sickle Cell Disease Publication Update
Stay current with the latest sickle cell research, regulatory updates, and guidelines.
Psychosocial Neglect and the Rise in Psychosis Among Adults With Sickle Cell Disease in Little Caribbean, NY
To evaluate the prevalence of psychosocial neglect and patterns of under-recognized psychosis among young adults with sickle cell disease (SCD) and to examine their impact on treatment, pain reduction, and...
A Standardized Sickle Cell Admission Order Set in the Electronic Medical Record to Improve Outcomes in Patients With Sickle Cell Pain Crisis: A Quality Improvement Project
To evaluate whether implementation of a standardized electronic medical record (EMR) admission order set could improve hospitalization outcomes for patients admitted with sickle cell pain crisis.
Clinical Predictors for the Variability of Urine Albumin Concentration in Patients With Sickle Cell Disease
To investigate whether vaso-occlusive episodes (VOE) and other clinical factors influence variability in urine albumin-to-creatinine ratio (UACR) in patients with sickle cell disease (SCD).
Fat Embolism Syndrome in Three Adolescents With Sickle Cell Disease
To describe clinical presentation, diagnostic challenges, and management of fat embolism syndrome (FES) in adolescents with sickle cell disease (SCD).
Comparative Assessment of Biologic (Flow Adhesion of Whole Blood to P-selectin) and Clinical Response to Crizanlizumab in a Real-world Clinical Setting
To evaluate whether a biologicmarker — flow adhesion of whole blood to P-selectin (FA-WB-PSEL) — correlates with clinical outcomes inpatients with sickle cell disease treated with crizanlizumab.
Altered Resting-State Functional Connectivity in Sickle Cell Disease: Insights Into Pain Sensitivity and Cerebral Hemodynamics
To investigate whether alterations in resting-state functional connectivity are associated with pain sensitivity and cognitive changes in sickle cell disease (SCD).
Non-Myeloablative Hematopoietic Cell Transplantation Improves Organ Morphology and Function in a Murine Model of Sickle Cell Disease
To assess whether non-myeloablative hematopoietic cell transplantation can affect the progression of multi-organ damage in a preclinical sickle cell disease model.
Correlation of Noninvasive Hemoglobin Measurement to Vaso-occlusive Crises in Patients With Sickle Cell Disease
To evaluate whether frequent home-based hemoglobin monitoring using nailbed optical measurement via a smartphone application could identify physiologic trends associated with the onset of vaso-occlusive crises in adults with sickle...
Levagen+ Ameliorates Hyperalgesia in a Mouse Model of Sickle Cell Disease
To evaluate whether palmitoylethanolamide (PEA), a non-intoxicating lipid mediator related to cannabinoid signaling, could reduce pain hypersensitivity and inflammatory activity in sickle cell disease (SCD).
Transition to Adult Sickle Cell Disease Care: A Project ECHO Learning Series for Healthcare Professionals
To evaluate whether a structured Project ECHO virtual learning series could improve healthcare professionals’ knowledge and confidence in facilitating transition from pediatric to adult care for patients with sickle cell...