Assess hemodynamic responses to mental and psychological stress in adults with sickle cell anemia (HbSS) using beat-to-beat blood pressure monitoring.
Assess hemodynamic responses to mental and psychological stress in adults with sickle cell anemia (HbSS) using beat-to-beat blood pressure monitoring.
To investigate whether hydroxyurea (HU) modulates expression of transcriptional repressors that silence fetal γ-globin genes, thereby clarifying the molecular mechanism of HbF induction.
To compare the ability of neutrophils from individuals with sickle cell anemia (SCA) versus controls to perform phagocytosis (uptake of foreign particles), and to assess how transfusion exposure affects neutrophil...
Evaluate preliminary validity of a daily functional status pain assessment (FSPA) tool for adults with sickle cell disease (SCD) during vaso-occlusive crises (VOCs), with the aim of enhancing discharge readiness...
To identify hematological, biochemical, and metabolic biomarkers associated with sickle cell anemia (SCA) severity and to assess machine learning models' ability to predict disease severity accurately.
Assess prevalence of nocturnal hemoglobin desaturation (NHD) among adults with severe sickle cell disease (SCD) who receive chronic red blood cell exchange (RCE) transfusions.
To examine the relationship between Adverse Childhood Experiences (ACEs) and asthma among children and adolescents with Sickle Cell Disease (SCD).
Retrospective study reviewed 81 pediatric SCD patients referred for polysomnography to explore factors associated with nocturnal hypoxemia (NH), independent of obstructive sleep apnea (OSA).
A recent study explored real-world experiences from a single-center case series of adults with sickle cell disease transitioned from full opioid agonists to buprenorphine for chronic pain management.